The color of serum can often be a point of confusion for researchers and distributors when purchasing. Why do different manufacturers produce serums with varying colors? What color is considered normal, and how can you tell if the serum is of good quality? Today, Shanghai Jinma will help clarify these questions.
According to our technical team's long-term analysis, the color of serum—whether yellow or red—is mainly influenced by the hemoglobin content. In China, the standard for serum used in cell culture is no more than 20mg/dl. However, the level of hemoglobin does not directly affect the serum's performance. Instead, it serves as an indicator of the blood collection process’s standardization. Proper handling during collection helps minimize hemolysis, resulting in a clearer, brighter serum.
In domestic serum production, blood collection points are often scattered, and many are collected right after slaughter, leading to minimal hemolysis. This results in a bright, waxy yellow color. It's worth noting that most domestic serum does not meet the strict definition of fetal bovine serum (FBS). On the other hand, imported serum tends to have some degree of hemolysis because the true serum has weaker coagulation ability, making red blood cells more prone to rupture.
Generally, domestically produced serum tends to appear slightly yellowish, while high-quality imported serum, such as Gibco 16000, often shows a deeper yellow or even orange-red. However, heat-inactivated serum or serum that has been improperly stored may lose its hemoglobin integrity, resulting in a dark red or brown appearance.
Shanghai Huding offers serum in various packaging sizes, including 100ml, 200ml, and 500ml, available under well-known brands like HyClone, GIBCO, NQBB, and Sigma. We ensure authenticity, stability, and reliable quality at competitive prices. Feel free to reach out for more information.
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